Melanotan peptides, specifically Melanotan 1 (MT-1) and Melanotan 2 (MT-2) are synthetic analogs of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). These peptides were initially developed for their potential to induce skin pigmentation and provide a tan without exposure to ultraviolet (UV) radiation. The primary purpose was to create a sunless tanning method, reducing the risks associated with traditional sun exposure.Â
Melanotan peptides work by stimulating melanocytes, the cells responsible for producing melanin, the pigment responsible for skin color. When administered, they activate melanocytes to produce more melanin, leading to increased pigmentation in the skin. This process mimics the natural tanning response that occurs in the body when exposed to sunlight.
Beyond their tanning effects, Melanotan peptides have been investigated for other potential benefits. Melanotan 2, in particular, has been studied for its ability to increase sexual arousal, reduce compulsive and addictive behaviors, suppress appetite, and potentially have effects on melanin production in the eyes.Â
PT-141 also called Bremelanotide (generic clinical name), is a heavily modified synthetic derivative of alpha-melanocyte-stimulating hormone. It has been tested in clinical trials as a treatment for both male/female hypoactive sexual desire disorder and acute hemorrhage. PT-141 is an agonist for the melanocortin-4 and melanocortin-1 receptors. Research shows that it promotes sexual arousal and stimulates the immune system.
Melanotan peptides are for research use only.Â
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